Therapeutic Options for Neonatal Acute Kidney Injury (AKI)

Acute Kidney Injury (AKI) biomarker.

The kidney has a remarkable capacity to withstand insults for an extended period of time. The sensitivities of individual renal cells to injury vary depending on their type, position in the nephron, local vascularization, and the nature of injury. The resulting kidney injury is a product of the interplay between cell dysfunction, cell death, proliferation, inflammation, and recovery. The Acute...

Acute Kidney Injury (AKI) in perinatal asphyxia

Background: Acute kidney injury (AKI) is a common consequence of perinatal asphyxia, occurring in upto 56% of these neonates. It is important to recognize AKI in asphyxiated neonates to facilitate administration of appropriate fluids and electrolytes in order to improve their outcome. Objectives: To determine the incidence of AKI in asphyxiated neonates and to correlate the severity and type of...

Neonatal Acute Kidney Injury.

In recent years, there have been significant advancements in our understanding of acute kidney injury (AKI) and its impact on outcomes across medicine. Research based on single-center cohorts suggests that neonatal AKI is very common and associated with poor outcomes. In this state-of-the-art review on neonatal AKI, we highlight the unique aspects of neonatal renal physiology, definition, risk ...

Acute Kidney Injury (AKI) and Management of Renal Tumors

Acute kidney injury (AKI) is characterized by a rapid decline in kidney function within a few hours or a few days. AKI is an independent risk factor for mortality in critically ill patients. Determination of the prevalence of AKI depends on the definition employed and on methods used for definite diagnosis. The incidence and prevalence of AKI vary with the clinical setting, based on separately ...

NGAL, the New Marker for Acute Kidney Injury